Phencyclidine Confirmation, Urine

CPT CODE:

USEFUL FOR:

Detection of drug abuse involving PCP (angel dust, or angel hair)

SPECIMEN REQUIRED:

20 mL from a random urine collection. No preservative. No specimen substitutions. No STATS are accepted for this procedure. Send specimen refrigerated in a plastic, 60-mL urine bottle. For situations where chain-of-custody is required, a Chain-of-Custody Kit (Supply T282) is available. For chain-of-custody information, see #9426 "Chain-of-Custody Processing."Note:    Additional drug panels and specific requests are available.Call Mayo Medical Laboratories at 800-533-1710 or 507-266-5700.

TRANSPORT TEMPERATURE:

Refrig\Frozen OK\Ambient <72 hours OK 

CLINICAL INFORMATION:

Phencyclidine (PCP) is a drug of abuse. This compound affects diverseneural pathways and interacts with cholinergic, adrenergic, GABA-secreting, serotoninergic, opiate neuronal receptors, and gamma receptors. It has analgesic, anesthetic, and stimulatory effects, giving bizarre behavior, ranging from depression through catatonia, euphoria, violent rage, and hallucinations. Most fatalities result from its hypertensive effect.
Diagnosis of PCP usage depends on drug screen. PCP is excreted in the urine.

CLINICAL INTERPRETATION:

The presence of PCP in urine at concentrations >25 ng/mL is a strong indicator that the patient has used PCP.

REFERENCE VALUES:

Negative

Positives are reported with a quantitative GC-MS result.

Cutoff concentrations:

IMMUNOASSAY SCREEN

      <25 ng/mL

PHENCYCLIDINE by GC-MS

      <25 ng/mL